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Despite the faster escalation, retatrutide achieves greater weight loss (24.2% at 48 weeks versus 22.5% at 72 weeks) due to the additional glucagon receptor activation that increases energy expenditure and fat mobilization
These drugs are not new, said Ziyad Al-Aly, who directs research and development at the St
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By structuring trials in this way, researchers were able to balance the competing demands of safety monitoring, patient comfort, and the scientific need to push towards therapeutically relevant doses
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